Dr. S. Sudhakar is a distinguished Professor of Biotechnology at Manonmaniam Sundaranar University, Tirunelveli, India, with more than three decades of experience in molecular biology, regeneration biology, genomics, and translational biotechnology research. He is internationally recognized for pioneering earthworm-based regeneration biology, genome sequencing, and stem cell–related discoveries with strong implications for regenerative medicine.
Online Profiles
Dr. Sudhakar’s scholarly work is indexed across major international scientific platforms including PubMed, Scopus, Web of Science, and GenBank, with extensive genome, transcriptome, and sequence submissions, alongside editorial board service and global research collaborations in the USA, Europe, and Asia.
Education
He obtained his Ph.D. in Molecular Biology from Madurai Kamaraj University (1999), following an M.Sc. in Microbiology (University Gold Medalist, 1992) and a B.Sc. in Chemistry with Zoology as ancillary, establishing a strong interdisciplinary foundation in biological sciences.
Research Focus
His research focuses on regeneration biology, stem cell biology, genome and transcriptome analysis, DNA repair mechanisms, riboflavin-mediated regeneration pathways, earthworm genomics, translational regenerative medicine, nanoparticle toxicology, and molecular mechanisms underlying tissue repair.
Experience
Dr. Sudhakar has served as Professor of Biotechnology since 2013 at Manonmaniam Sundaranar University, previously as Associate Professor and Head, and has held prestigious postdoctoral and research associate positions at the University of Texas Health Science Center at San Antonio, University of California Irvine, and University of Southern California, Los Angeles.
Research Timeline & Research Contributions
His research trajectory evolved from viral genomics and molecular regulation of transcription to DNA damage response and aging pathways, and later to groundbreaking regeneration biology using earthworms, culminating in whole-genome sequencing, multi-tissue transcriptomics, and identification of over 21,550 genes relevant to regenerative medicine.
Research Impact
Dr. Sudhakar has published over 51 peer-reviewed research papers, authored 4 books, holds 3 patents, and has deposited 10 genome and transcriptome sequences in international repositories, significantly influencing regeneration biology, genomics, molecular medicine, and environmental biotechnology.
Innovation & Intellectual Property
He is an inventor on multiple Indian patents, including novel anti-tuberculosis drug candidates, antimicrobial compositions, and bioactive formulations, demonstrating translational innovation bridging molecular biology, drug discovery, and public health.
Research Projects & Funding
Dr. Sudhakar has successfully led and executed numerous competitive research projects funded by UGC, DBT, DST-SERB, and INSPIRE programs, covering regenerative biology, lamin A molecular mechanisms, cancer diagnostics, transcriptomics, bioinformatics infrastructure, and advanced biotechnology education.
Conference Contributions
He has delivered over 380 invited lectures worldwide and coordinated more than 30 national and international conferences, workshops, and training programs, significantly advancing scientific communication, patent awareness, bioinformatics capacity building, and regeneration biology dissemination.
Academic Excellence
His academic excellence is reflected in national first rank achievements, prestigious fellowships from DBT and UGC, Best Research Award at the University of California Irvine, and multiple national and international honors including Tamil Scientist Award, Most Inspiring Faculty Award, and Bharath Shiksha Rathna Award.
Societal / Industry Contribution
Dr. Sudhakar’s research has directly addressed societal challenges, including the identification and control of pathogenic outbreaks in livestock that prevented major economic losses, promotion of scientific literacy through public engagement, and translational research benefiting agriculture, medicine, and environmental safety.
Global Recognition
With long-term international research collaborations, high-impact publications, genome submissions, patents, and leadership roles in academic governance and editorial boards, Dr. Sudhakar is globally recognized as a leading authority in regeneration biology and molecular biotechnology.
Publications
Sudhakar, S., Sun, X., Pan, Y.R., & Lee, E.Y.H.P. Cep164 is a mediator protein for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1, Genes & Development, 22, 587–600 (2008).
Comez, H., Sudhakar, S., & Comai, L. Perturbation of wild-type Lamin A metabolism results in accelerated aging phenotype, Aging Cell, 7(3), 355–367 (2008).
Elaiya Raja, S., et al., Function of translationally controlled tumor protein in regeneration, PLoS ONE, 12(4), e0175319 (2017).
Sayan, P., et al., The transcriptome of anterior regeneration in earthworm Eudrilus eugeniae, Molecular Biology Reports, 47, 1–25 (2020).
Arun, A., et al., Draft genome sequence of the earthworm Eudrilus eugeniae, Current Genomics, 23(2), 118–125 (2022).
Paul, S., et al., Importance of clitellar tissue in regeneration of earthworm, Functional & Integrative Genomics, 22(4), 1–32 (2022).
Paul, K., et al., Impact of engineered silver nanoparticles on Eudrilus eugeniae, Environmental Science and Pollution Research, 2022.
Raj, A.P.M.S., et al., Genetic signatures of exceptional longevity, Human Genomics, 19, 115 (2025).
(Dr. Sudhakar has authored over 50 SCI/Scopus indexed research articles; full list available upon request.)
Books
Sudhakar, S. & Mathavan, S. Viral Pesticides for Environmental Safety, Phoenix Publishing House, New Delhi, 1998.
Sudhakar, S. Research Methods in Life Sciences, Bharathidasan University, 2011.
Sudhakar, S. Importance of Research and Innovations in Emerging Countries, ACE International, 2020.
Kanniah, P., et al., Benign Fabrication of Nanoparticles from Algae, Elsevier, 2022.