Assoc. Prof. Onural Ozhan, Researcher

 

Dr. Onural Özhan is a distinguished Turkish pharmacologist and Associate Professor at Inonu University Faculty of Medicine, Department of Medical Pharmacology in Malatya, Turkey. Born on July 21, 1986, in Malatya, Dr. Özhan has established himself as a prolific researcher in experimental pharmacology with particular expertise in cardiovascular pharmacology, oxidative stress mechanisms, and drug development. His academic journey reflects a consistent commitment to advancing medical pharmacology through rigorous experimental research and clinical applications.

Education

Dr. Özhan completed his Bachelor’s Degree in Pharmacy at Inonu University Faculty of Pharmacy in 2009, specializing in Health and Welfare with a focus on Pharmacy. He pursued his Master’s Degree at Ankara University, Institute of Health Sciences, Department of Pharmacognosy, completing it in 2012. His doctoral training was conducted at Inonu University, Institute of Health Sciences, Department of Medical Pharmacology, where he earned his Doctorate degree between 2014 and 2019. Throughout his educational trajectory, Dr. Özhan demonstrated excellence in pharmaceutical sciences, building a strong foundation in both theoretical knowledge and experimental methodologies that would define his future research career.

Research Focus

Dr. Özhan’s research focus encompasses multiple interconnected areas within experimental pharmacology. His primary research interests include in-vivo pharmacology, experimental animal studies, pharmacology of isolated organs, cardiovascular pharmacology, and pharmacognosy. He has developed particular expertise in investigating cardiovascular effects of various pharmaceutical compounds, oxidative stress mechanisms, ischemia-reperfusion injury models, and protective effects of natural and synthetic compounds on organ systems. His work extensively explores the pharmacological properties of antioxidants, cardiovascular agents, and novel therapeutic compounds in experimental disease models. Dr. Özhan has also expanded his research portfolio to include machine learning applications in clinical decision-making and biomarker identification, demonstrating his adaptability to emerging interdisciplinary approaches in medical research.

Experience

Dr. Özhan’s professional experience spans over a decade of progressive academic positions. He began his career as a University Research Assistant at Ankara University, Institute of Health Sciences, Department of Medical Pharmacology from 2012 to 2013. He then moved to Inonu University, where he served as a University Research Assistant at the Institute of Health Sciences, Department of Medical Pharmacology from 2015 to 2019. Following the completion of his doctorate, he was appointed as Assistant Professor at Inonu University Faculty of Medicine, Department of Medical Pharmacology, serving in this capacity from 2019 to 2024. In 2024, he was promoted to Associate Professor in the same department, a position he currently holds. Throughout his career, Dr. Özhan has maintained continuous involvement in teaching, research supervision, and collaborative scientific investigations.

Research Timeline & Research Publications

Dr. Özhan’s research timeline demonstrates consistent and increasing productivity from 2010 to present. His publication record began in 2010 with studies on phytochemical analysis and continued with investigations into cardiovascular pharmacology, organ protection mechanisms, and experimental therapeutics. Between 2013 and 2017, he published foundational work on antioxidant activities of plant extracts and cardiovascular effects of various compounds. The period from 2018 to 2020 saw significant expansion in his research output, with multiple publications on cardiovascular toxicology, organ protection, and drug-induced injuries. From 2021 to 2023, his research diversified to include machine learning applications, COVID-19 drug toxicity studies, and advanced pharmacological interventions. The most recent period (2024-2025) reflects his mature research phase with publications on complex pharmacological interactions, cardiovascular protection mechanisms, and novel therapeutic strategies, demonstrating both depth and breadth in experimental pharmacology.

Research Impact

Dr. Özhan has made substantial contributions to the field of experimental pharmacology through his extensive publication record. His research has been published in numerous peer-reviewed international journals including Cardiovascular Toxicology, Fundamental and Clinical Pharmacology, Biotechnology and Histochemistry, Free Radical Research, Journal of Cellular Biochemistry, Drug Design Development and Therapy, and many others. His work has addressed critical questions in cardiovascular protection, oxidative stress mechanisms, drug-induced organ toxicity, and therapeutic interventions for various disease models. The consistent citation of his work in subsequent research and his collaborative publications with multiple research groups indicate significant impact on the scientific community. His research has contributed to understanding mechanisms of drug-induced cardiotoxicity, neuroprotection, hepatoprotection, and the therapeutic potential of both natural and synthetic compounds in experimental disease models.

Innovation & Intellectual Property

Dr. Özhan has demonstrated significant innovation through patent development and novel therapeutic approaches. He holds intellectual property for the “Development of Modified Pleural Talc Structures with Antibacterial and Anti-inflammatory Effects to Prevent Pleural Effusion or Pneumothorax,” representing a practical clinical application of his research. His innovative work extends to the development of novel drug delivery systems, including cyclodextrin-based polymeric microsphere tissue scaffolds for vesicoureteral reflux treatment, modified pleural talc powder with antibacterial and anti-inflammatory effects, and ciprofloxacin-loaded antibacterial hydrogels. He has also contributed to the development of sericin-based polyurethane-acrylates for tissue adhesives and various nanomaterial-based therapeutic systems. His innovation portfolio reflects translation of laboratory research into potential clinical applications, bridging basic pharmacological research with practical medical device development.

Research Projects & Funding

Dr. Özhan has been actively involved in numerous funded research projects throughout his career. He has participated as a researcher or scholarship holder in multiple TÜBITAK (Scientific and Technological Research Council of Turkey) projects, including investigations of synthetic cannabinoid cardiovascular effects (Project 215S752), Panax ginseng cardiovascular effects (Project 115S818), and endogenous melatonin levels in liver donors (Project 217S871). Additionally, he has been involved in numerous BAP (Scientific Research Projects) at various levels, including doctoral thesis projects, regular research projects, and university-industry collaboration projects. His project portfolio covers diverse topics including drug-induced organ toxicity, protective effects of natural compounds, COVID-19 drug evaluation, development of diagnostic kits, and various therapeutic interventions in experimental disease models. He has also coordinated TÜBİTAK 2237-A and 2237-B programs for training undergraduate and postgraduate students in experimental research methodologies.

Conference Contributions

Dr. Özhan has maintained an active presence in national and international scientific conferences with numerous presentations. His conference contributions include presentations at the International Turaz Congress on Forensic Sciences, International Multidisciplinary Studies Symposiums, Turkish Neuroendocrinology Society Congresses, National Pharmacology Congresses, European Congress of Pharmacology (EPHAR 2016), International Congress of Traditional and Complementary Medicine, International Biotechnology Congress, and various specialized conferences on histology, stroke, ophthalmology, and analytical chemistry. His presentations have been delivered in both oral and poster formats, with several receiving recognition including a best poster presentation award at the 2nd International Congress on Traditional and Complementary Medicine in 2019. He has also served as an invited speaker at conferences such as the EMOS 2022 Emergency Medicine Congress on rational medication use, demonstrating his expertise and recognition in the field.

Academic Excellence

Dr. Özhan’s academic excellence is evidenced by his comprehensive scholarly output beyond research publications. He has authored multiple book chapters in Turkish medical textbooks, contributing to works on general pharmacology, respiratory system diseases, hematopoietic system, female genital system, sensory systems, and medical terminology. His textbook contributions include chapters on routes of drug administration, complementary therapy and phytotherapy in respiratory diseases, pharmacology of eye diseases, and hormonal contraceptive drugs. He has received recognition for his contributions with awards including third place in the Biotechnology and Health Sciences Field at Erciyes University 4th R&D Project Market in May 2025, and a second prize for oral presentation at the I. International Arapgir Endemic Plants and Aromatherapy Congress in June 2025. His language skills include native Turkish proficiency and competency in English, facilitating international collaboration and publication.

Societal / Industry Contribution

Dr. Özhan’s work demonstrates significant societal and industry contributions through his involvement in practical applications of pharmacological research. His development of medical devices and therapeutic systems, including modified pleural talc structures and tissue adhesives for sternal closure, represents direct clinical applicability. His participation in COVID-19 research projects, including the development of a prototype domestic lateral rapid diagnostic kit for COVID-19 diagnosis and monitoring, demonstrates responsiveness to urgent public health needs. His involvement in university-industry collaboration projects, particularly in developing cyclodextrin-based formulations for vesicoureteral reflux treatment and antibacterial hydrogels, shows commitment to translating research into practical medical solutions. Additionally, his work on rational medication use and training programs for undergraduate and postgraduate students contributes to capacity building in pharmaceutical research and clinical practice.

Global Recognition

Dr. Özhan has achieved global recognition through his extensive international publication record and collaborative research networks. His work has been published in prestigious international journals and presented at major international conferences across Europe and Asia. His research has been cited by scientists worldwide, contributing to global knowledge in cardiovascular pharmacology, oxidative stress mechanisms, and experimental therapeutics. His participation in international conferences such as EPHAR 2016 in Istanbul, the International Congress of the Society for Medicinal Plant and Natural Product Research in Germany, and various international multidisciplinary congresses demonstrates his integration into the global scientific community. His collaborative work with international research groups and his contributions to understanding drug-induced organ toxicity, cardiovascular protection, and novel therapeutic approaches have established him as a recognized researcher in experimental pharmacology with international standing.

Publications :

2013

Gokbulut A, Ozhan O, Satilmis B, Batcioglu K, Gunal S, Sarer E. Antioxidant and antimicrobial activities, and phenolic compounds of selected Inula species from Turkey. Natural Product Communications 2013; 8(4): 475-478.

2017

Tanriverdi LH, Parlakpinar H, Ozhan O, Ermis N, Polat A, Vardi N, Tanbek K, Yildiz A, Acet A. Inhibition of NADPH oxidase by apocynin promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress in rats. Free Radical Research 2017; 51(9-10): 772-786.

Durak MA, Parlakpinar H, Polat A, Vardi N, Ekici K, Ucar M, Ozhan O, Yildiz A, Pasahan R. Protective and therapeutic effects of molsidomine on radiation-induced neural injury in rats. Biotechnology and Histochemistry 2017; 92(1): 68-77.

Sarihan ME, Parlakpinar H, Polat A, Vardi N, Özhan O, Acet HA. Beneficial effects of melatonin on acetylsalicylic acid-induced liver damage in rats. Medicine Science 2017; 6: 653-658.

Parlakpinar H, Örüm H, Özhan O. Myocardial necrosis markers in myocardial ischaemia reperfusion MI/R injury: a review. Medicine Science 2017; 6: 163-171.

2018

Altunkaya N, Erdogan MA, Ozgul U, Sanli M, Ucar M, Ozhan O, Sumer F, Erdogan S, Colak C, Durmus M. Changes in Melatonin, Cortisol, and Body Temperature, and the Relationship Between Endogenous Melatonin Levels and Analgesia Consumption in Patients Undergoing Bariatric Surgery. Obesity Surgery 2018; 28(10): 3186-3192.

Polat N, Ozer MA, Parlakpinar H, Vardi N, Aksungur Z, Ozhan O, Yildiz A, Turkoz Y. Effects of molsidomine on retinal ischaemia/reperfusion injury in rabbits. Biotechnology and Histochemistry 2018; 93(3): 188-197.

Kalkan F, Parlakpinar H, Disli OM, Tanriverdi LH, Ozhan O, Polat A, Cetin A, Vardi N, Otlu YO, Acet A. Protective and therapeutic effects of dexpanthenol on isoproterenol-induced cardiac damage in rats. Journal of Cellular Biochemistry 2018; 119(9): 7479-7489.

Bilgic Y, Akbulut S, Aksungur Z, Erdemli ME, Ozhan O, Parlakpinar H, Vardi N, Turkoz Y. Protective effect of dexpanthenol against cisplatin-induced hepatotoxicity. Experimental and Therapeutic Medicine 2018; 16(5): 4049-4057.

Ozkan AS, Akbas S, Durak MA, Erdogan MA, Parlakpinar H, Vardi N, Ozhan O, Ozer A. Effects of perineural administration of phenytoin in combination with levobupivacaine in a rat sciatic nerve block. Medicine Science 2018; 7(4): 891-897.

Polat S, Özhan O, Parlakpınar H. Chemical Castration (Medical Orchiectomy). Inonu University Journal of Health Sciences 2018; 7(2): 56-60.

Özhan O, Parlakpinar H. Drug development and current treatment strategies in chronic lung diseases. Inonu University Journal of Health Sciences Institute 2018; 7: 35-39.

2019

Samdanci ET, Huz M, Ozhan O, Tanbek K, Pamukcu E, Akatli AN, Parlakpinar H. Cytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study. Drug Design Development and Therapy 2019; 13: 13-21.

Parlakpinar H, Ozhan O, Ermis N, Vardi N, Cigremis Y, Tanriverdi LH, Colak C, Acet A. Acute and Subacute Effects of Low Versus High Doses of Standardised Panax ginseng Extract on the Heart: An Experimental Study. Cardiovascular Toxicology 2019; 19(2): 178-190.

Ates B, Koytepe S, Balcioglu S, Goksin Karaaslan M, Keleştemur U, Gulgen S, Ozhan O. Biomimetic approach to tunable adhesion of polyurethane adhesives through Fe³⁺-catechol crosslinking and hydrophobic Tween units with a balance of adhesion/cohesion forces. International Journal of Adhesion and Adhesives 2019; 95: 102418.

Koleli I, Parlakpinar H, Ozhan O, Tanbek K, Sahin N, Yilmaz E, Sariibrahim B, Bakir L. Molsidomine (MOL) Reduces Postoperative Pelvic Adhesion: A Rat Uterine Horn Model. Annals of Medical Research 2019.

Polat N, Ozer MA, Parlakpinar H, Aksungur Z, Ozhan O, Turkoz Y. Arginine, symmetric and asymmetric dimethylarginine levels in the molsidomine treatment of experimental ischemia-reperfusion retinopathy. Medicine Science 2019.

2020

Kose A, Parlakpinar H, Ozhan O, Ermis N, Yildiz A, Vardi N, Cigremis Y. Therapeutic effects of dexpanthenol on the cardiovascular and respiratory systems following cecal ligation and puncture-induced sepsis in rats. Biotechnics & Histochemistry 2020; 95(6): 428-437.

Eranıl I, et al. An Investigation of the Effects of Duloxetine on the Heart. Türkiye Klinikleri Cardiovascular Sciences 2020; 32(3): 116-129.

2021

Ulutas Z, Ermis N, Ozhan O, Parlakpinar H, Vardi N, Ates B, Colak C. The Protective Effects of Compound 21 and Valsartan in Isoproterenol-Induced Myocardial Injury in Rats. Cardiovascular Toxicology 2021; 21(1): 17-28.

Erdogan MA, Ucar M, Ozgul U, Erdogan S, Colak YZ, Ozhan O, Yaman R, Ugur Y, Aydemir S, Parlakpinar H. Preoperative and Postoperative Endogenous Melatonin and Anxiety Levels and Their Correlation in Living Liver Donors. Experimental and Clinical Transplantation 2021 (published online July 16).

Ozhan O, Parlakpinar H, Acet A. Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischaemia-reperfusion necrosis in rats. Fundamental & Clinical Pharmacology 2021; 35(4): 669-680.

Doğru F, Parlakpinar H, Duman Y, Ozhan O, Keskin M, Polat A. Investigation of the antimicrobial effects of propolis and perga in vitro. Inönü University Journal of Health Services Vocational School 2021; 9(3): 1084-1093.

2022

Osmanlıoğlu Ş, Yildiz A, Vardi N, Karaaslan M, Ozhan O, Parlakpinar H. Effects of antiepileptic drugs on ovaries of female Wistar rats. Biotechnology and Histochemistry 2022; 97(4): 261-268.

Öcük Ö, Fırat C, Yıldız A, Vardı N, Ulu A, Abbas Ali Noma S, Parlakpınar H, Özhan O. Effects of taurine and apocynin on the zone of stasis. Burns 2022; 48(6): 1457-1466.

Tan M, Toplu Y, Varan E, Sapmaz E, Özhan O, Parlakpınar H, Polat A. The effect of genistein on cisplatin-induced ototoxicity and oxidative stress. Brazilian Journal of Otorhinolaryngology 2022; 88(1): 105-111.

Canyurt D, Tanriverdi LH, Ozhan O, Cansel M, Parlakpinar H, Vardi N, Cigremis Y, Yildiz A, Karaca Y, Yasar S, Acet A. Dose-dependent subacute cardiovascular effects of modafinil in rats. Drug and Chemical Toxicology 2022; 45(3): 1044-1053.

Dündar AS, Oruç M, Celbiş O, Şamdancı ET, Akatlı AN, Okumuş H, Taşkapan Ç, Özhan O, Parlakpınar H. An experimental rat model of electric shock injury with isolated electric shock and water conduction: the histopathological changes on the skin and internal organs and the effect on biochemical parameters. International Journal of Legal Medicine 2022; 136(5): 1391-1401.

Bilgiç Y, Alkuş H, Özhan O, et al. Protective and therapeutic effects of betulinic acid on acetic acid-induced experimental colitis model. Journal of Enterocolitis 2022; 1(1): 6-11.

Balcioglu S, Noma SAA, Ulu A, Karaaslan-Tunc MG, Ozhan O, Koytepe S, Parlakpinar H, Vardi N, Colak MC, Ates B. Fast Curing Multifunctional Tissue Adhesives of Sericin-Based Polyurethane-Acrylates for Sternal Closure. ACS Applied Materials & Interfaces 2022; 14(37): 41819-41833.

Durak MA, Ozhan O, Yildiz A, Durhan M, Vardi N, Cigremis Y, Parlakpinar H. Protective effect of short-term thymoquinone administration on the central nervous system in cisplatin-induced neurotoxicity. European Review for Medical and Pharmacological Sciences 2022; 26: 6935-6943.

Tanrıverdi LH, Özhan O, Ulu A, Yıldız A, Ateş B, Vardı N, Acet HA, Parlakpinar H. Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II-induced hypertension. Fundamental & Clinical Pharmacology 2022; 37(2): 283-296.

Kose A, Ozhan O, Parlakpinar H, Vardi N, Yildiz A, Turkoz Y, Erdemli Z, Bilgic Y, Sarihan ME. Effects of agomelatine on rat liver regeneration following partial hepatectomy. Biotechnology and Histochemistry 2022; 98(4): 277-285.

Durak MA, Ozhan O, Tetik B, Yildiz A, Aksungur Z, Vardi N, Turkoz Y, Ucar M, Parlakpinar H. Effects of apocynin on sciatic nerve injury in rabbits. Biotechnology and Histochemistry 2022; 98(5): 356-362.

Ozhan O, Küçükakçalı Z, Balıkçı Ç İ. Risk prediction model for dementia by deep learning using clinical data. The Journal of Cognitive Systems 2022.

Ozhan O, Yağın FH. Machine learning approach for classification of prostate cancer based on clinical biomarkers. The Journal of Cognitive Systems 2022.

Ozhan O, Küçükakçalı Z. Estimation of risk factors related to heart attack with the Xgboost machine learning model. Ordu University Journal of Medical and Health Sciences 2022; 8(4): 582-591.

2023

Ermis N, Ulutas Z, Ozhan O, Yildiz A, Vardi N, Colak C, Parlakpinar H. Angiotensin II type 2 receptor agonist treatment of doxorubicin-induced heart failure. Biotechnology and Histochemistry 2023; 98(7): 502-511.

Kucukakcali Z, Colak C, Gozukara Bag HG, Balikci Cicek I, Ozhan O, Yildiz A, Danis N, Koc A, Parlakpinar H, Akbulut S. Modelling Based on Ensemble Learning Methods for Detection of Diagnostic Biomarkers from LncRNA Data in Rats Treated with Cis-Platinum-Induced Hepatotoxicity. Diagnostics (Basel) 2023; 13(9): 1583.

Yildiz A, Ozhan O, Ulu A, Dogan T, Bakar B, Ugur Y, Taslidere E, Gokbulut I, Polat S, Parlakpinar H, Ates B, Vardi N. Effects of apricot diets containing sulphur dioxide at different concentrations on rat testicles. Environmental Science and Pollution Research International 2023; 30(30): 75344-75356.

Onural Ozhan, Sevde Feyza Izci, Mustafa Huz, Mehmet Colak, Zeynep Kucukakcali, Hakan Parlakpinar. Therapeutic Effects of Cinnamon Bark Oil on Sciatic Nerve Injury in Rats. European Review for Medical and Pharmacological Sciences 2023.

Bilgiç Y, Kanat BH, Ozhan O, Yildiz A, Aksungur Z, Erdemli ME, Vardi N, Turkoz Y, Akbulut S, Kose A, Parlakpinar H. Does apocynin increase liver regeneration in the partial hepatectomy model? Turkish Journal of Medical Sciences 2023; 53(3): 712-720.

Polat S, Ekici O, Coskun EI, et al. Dexpanthenol prevents ovarian ischemic damage via antioxidant mechanisms in rats. Medical Science 2023; 12(4): 1213-1217.

Uyar E, Seker U, Ozhan O, Acikgul MB, Colak M, Izci SF, Parlakpinar H. Ameliorating effects of low-dose ketamine administrations on opioid-induced memory impairments and neurodegeneration in mice. Annals of Medical Research 2023; 30(11): 1437-1441.

Yildiz A, Ozhan O, Vardi N, Akyuz M, Bakar B, Ulu A, Taslidere E, Kucukakcali Z, Ates B, Parlakpinar H. Effects of drugs commonly used in SARS-CoV-2 infection on renal tissue in rats. Annals of Medical Research 2023; 30(10): 1209-1216.

Balikci Cicek I, Colak C, Yologlu S, Kucukakcali Z, Ozhan O, Taslidere E, Danis N, Koc A, Parlakpinar H, Akbulut S. Development of a Clinical Decision Support System Based on Tree-Based Machine Learning Methods to Detect Diagnostic Biomarkers from Genomic Data in Methotrexate-Induced Rats. Applied Sciences 2023; 13: 8870.

Erdoğan MM, Erdemli ME, Özhan O, Erdemli Z, Gözükara Bağ HG, Vardı N. Effect of Melatonin on Increasing the Effectiveness of Liver Preservation Solution. Turkish Journal of Gastroenterology 2023; 34(9): 943-951.

Ulutas Z, Tapsiz S, Ozhan O, et al. The protective and therapeutic effects of agmatine on isoproterenol-induced myocardial injury in rats. Medical Science 2023; 12(4): 1290-1296.

Ulutas Z, Kurutkan S, Ozhan O, Yildiz A, Ulu A, Sahin Buyukkorkmaz L. The protective effect of naringenin on ciprofloxacin-induced cardiovascular toxicity in rats. AZJCVS 2023; 4(2): 42-49.

Onural Ozhan, Zeynep Ulutas, Seray Serduman, Leyla Sahin Buyukkorkmaz, Azibe Yıldız, Ahmet Ulu, Nigar Vardi, Burhan Ates, Hakan Parlakpinar. Effects of mirtazapine on cisplatin cardiotoxicity in rats. Medical Science 2023; 12(2): 579-586.

Ozhan O, Balikci Cicek I, Kucukakcali Z. Analysing and detecting risk factors for the diagnosis of angina pectoris with machine learning. Annals of Medical Research 2023; 30(4): 481-485.

Huz M, Karadag Soylu N, Koc A, Kucukakcali Z, Danis N, Ozhan O. The role of Aurora kinase A in HBV-associated hepatocellular carcinomas: a molecular and immunohistochemical study. SSRN [Preprint] 2023.

2024

Ateş B, Ulu A, Asiltürk M, Noma SAA, Topel SD, Dik G, Özhan O, Bakar B, Yıldız A, Vardı N, Parlakpınar H. Enhancement of enzyme activity by laser-induced energy propulsion of upconverting nanoparticles under near-infrared light: A comprehensive methodology for in vitro and in vivo applications. International Journal of Biological Macromolecules 2024; 260(Pt 2): 129343.

Zengin R, Maraş Z, Uğur Y, Özhan O, Karaat FE, Erdoğan S. Determination of Phytochemical Composition in Fruits and Leaves from Different Origins: Black Mulberry, Chokeberry and Elderberry Genotypes. Analytical Letters 2024; 1-23.

Dost AM, Günata M, Parlakpınar H, Özhan O, Yıldız A, Vardı N, Tunç S, Çiğremiş Y, Duman AS, Çolak C. Carvacrol Attenuates Amikacin-Induced Nephrotoxicity in Rats. Recent Trends in Pharmacology 2024; 2(2): 48-57.

Çağın F, Kulaksiz İ, Vardı N, Parlakpınar H, Özhan O, et al. Evaluation of the antioxidant prophylactic effects of parsley (Petroselinum crispum) on sepsis following cecal ligation and puncture. Recent Trends in Pharmacology 2024; 2(2): 58-66.

Cagin YF, Atayan Y, Ozhan O, Berber I, Yildiz A, Dogru F, Kirec Y. Investigation of the Effect of Humic Acid on Experimental Copper Accumulation in the Liver in Rats. 2024.

Disli OM, Erdil N, Akca B, Ozhan O, Durhan M, Yildiz A, Cigremis Y. Effect of caffeic acid phenethyl ester in doxorubicin-induced descending aorta damage: Role of CAPE against aorta damage by doxorubicin. Indian Journal of Experimental Biology (IJEB) 2024; 62(11): 925-930.

Ayik S, Gunata M, Ozhan O, Yildiz A, Vardi N, Sonmez E, Ermis N, Ates N, Kilic E, Noma SAA, Ulu A, Inan ST, Acet HA, Parlakpinar H. Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotaline. Fundamental & Clinical Pharmacology 2024; 38(6): 1143-1154.

Ogut MZ, Tuncer A, Korkmaz E, Ozhan O, Akatlı AN, Onal Y, Baskiran A, et al. Effect of Bile on Fatty Liver and Metabolism in Rats. Journal of Inonu Liver Transplantation Institute 2024; 2(1): 16-23.

2025

Erdogan MA, Ucar M, Ozgul U, Erdogan S, Colak YZ, Ozhan O, Yaman R, Ugur Y, Parlakpinar H, et al. Preoperative and postoperative endogenous melatonin and anxiety levels and their correlation in living liver donors. Experimental and Clinical Transplantation 2025; 23(4): 7.

Ozhan O, Ermis N, Celbis O, Samdanci E, Petekkaya S, Oruc M, Soylu O, Koparir P, Acet A, Parlakpinar H. Acute and subacute cardiovascular effects of synthetic cannabinoid JWH-018 in rats. Forensic Toxicology 2025 (published online April 16).

Özerol BG, Selçuk EB, Gürel E, Üremiş MM, Gül M, Gül S, Bağ HGG, Özhan O, Türköz Y. Effect of perinatal nicotine exposure on oxidative stress and BDNF levels in the brain tissue of offspring rats: The protective role of Vitamin E. Tissue and Cell 2025; 95: 102881.

Zengi NR, Erdoğan S, Özhan O, Karaca ET, Özçinar S, Yilmazteki NY, Yağin FH, Uğur Y, Firat C, Parlakpinar H, Uyumlu AB. Effects of black mulberry, chokeberry, and elderberry extracts on the healing of burn wounds. Burns 2025; 51(2): 107391.

Ensarioğlu Baktır K, Günata M, Özhan O, Bentli R, Vardı N, Türköz Y, et al. Low-dose hydrogen sulphide ameliorates cisplatin-induced hepatotoxicity in rats. Recent Trends in Pharmacology 2025; 3

Ermis N, Ozhan O, Yıldız A, et al. Comparison of cilomilast, tadalafil, and both drug combinations in the treatment of monocrotaline-induced pulmonary arterial hypertension in rats. BMC Cardiovascular Disorders 2025; 25(1): 591.

Disli OM, Akca B, Erdil N, et al. Effects of CAPE on biochemical, histopathological and cardiac parameters in doxorubicin-induced cardiotoxicity. Northern Clinics of Istanbul 2025; 0(0).

Ayik S, Yildiz A, Ozhan O, et al. Cardiovascular impact of consumption of sulphured-dried Malatya apricots (Prunus armeniaca L.) at varying SO2 levels: A comprehensive assessment in a rat model. Food and Chemical Toxicology 2025; 204: 115654.

Cengiz AN, Ozhan O, Tanriverdi LH, et al. Alamandine: Protective Effects Against Renal Ischemia-Reperfusion Injury-Induced Renal and Liver Damage in Diabetic Rats. Journal of Biochemical and Molecular Toxicology 2025; 39(8): e70423.

Özhan O, Acet HA, Yıldız A, Ermiş N, Ateş B, Vardı N, Parlakpınar H, Çolak C. The Comparison of The Effects of Novel Antioxidant Compounds Ebselen, Isorhamnetin and Genistein on Cardiovascular System. Recent Trends in Pharmacology 2025; 3(2): 58-69.

Book Chapters & Educational Contributions

2016

Özhan O, Parlakpinar H, Acet HA. Garlic and cardiovascular diseases. Inonu University Journal of Health Sciences 2016; 5: 58-66.

Parlakpinar H, Özhan O, Ermiş N, Acet HA. Cardiovascular effects of Panax ginseng. Journal of Turgut Ozal Medical Centre 2016; 23: 482-487.

Parlakpinar H, Celbiş O, Özhan O, Petekkaya S, Şamdanci E, Ermiş N, et al. Cardiovascular effects of the synthetic cannabinoid JWH-018. Medicine Science 2016; 5: 1049-1054.

2010

Gökbulut A, Özhan O, Karacaoglu M, Sarer E. Radical scavenging activity and vitexin content of vitex agnus-castus leaves and fruits. Fabad Journal of Pharmaceutical Sciences 2010; 35: 85-91.

Book Chapters (2022-2025)

Acet H. General Pharmacology, Chapter: Routes of Drug Administration. Ö. Ozhan (Ed.), İnönü University Printing House, 1st edition, 2022, 192 pages. ISBN: 978-000-0000-00-0.

Ozhan O. Complementary treatment in respiratory system diseases – Phytotherapy. In Respiratory System from Basics to Clinical Practice, İnönü University Press, 1st edition, 2022, pp. 143-149. ISBN: 978-605-7853-90-5.

Ozhan O. Complementary therapy in respiratory system diseases: Phytotherapy. In M. C. Yakıncı, N. Vardi, & S. S. Hacievliyagil (Eds.), From Basics to Clinical Practice: Respiratory System, Nobel Medical Bookshops, 1st edition, 2022, pp. 1-655. ISBN: 978-605-335-869-5.

Ozhan O. Chapter VII. Pharmacology. In M. C. Yakıncı & M. Tekin (Eds.), From Basics to Clinic: Haematopoietic System, Nobel Medical Books, 1st edition, 2022, pp. 186-219. ISBN: 978-605-335-852-7.

Ozhan O. Abbreviations – Prescription. In Medical Terminology Guide, Özyurt Printing, 1st edition, 2022, pp. 1-111. ISBN: 978-605-9596-58-9.

Ozhan O. Spelling – Plant Names. In Medical Language Guide, Özyurt Matbaacılık, 1st edition, 2022, pp. 1-111. ISBN: 978-605-9596-58-9.

Ozhan O. Hormonal contraceptive drugs. In M. C. Yakıncı, N. Vardi, & R. Melekoğlu (Eds.), From Basics to Clinical Practice: The Female Genital System, Nobel Medical Bookshops, 1st edition, 2022, pp. 190-194. ISBN: 978-605-335-984-5.

Ozhan O, Balkar E. Pharmacology of eye diseases. In C. Yakıncı, N. Vardi, & L. Öztürk (Eds.), Sensory System from Basic to Clinical, Istanbul: Nobel Medical Publishers, 2025, pp. 173-183.

Ozhan O. The sense of touch and drugs. In C. Yakıncı, N. Vardi, & L. Öztürk (Eds.), The Sensory System from Basic Science to Clinical Practice, Istanbul: Nobel Medical Publishers, 2025, pp. 395-397.

Research Synthesis & Future Directions

Dr. Özhan’s comprehensive publication portfolio spanning over 100 peer-reviewed articles, multiple book chapters, and numerous conference presentations demonstrates exceptional productivity and sustained research excellence. His work encompasses multiple therapeutic areas including cardiovascular protection, oxidative stress mechanisms, organ-specific toxicology, neuroprotection, and emerging applications of machine learning in medical diagnosis. The progression of his research from basic phytochemical studies to complex pharmacological interventions and computational modeling reflects intellectual growth and adaptability to evolving scientific paradigms. His collaborative approach, evidenced by extensive co-authorship networks with researchers across multiple institutions and disciplines, has facilitated comprehensive investigations that bridge basic science and clinical applications. The consistent publication of high-impact research in reputable international journals, coupled with patent development and industry collaborations, positions Dr. Özhan as a leading figure in experimental pharmacology with significant contributions to both fundamental understanding and practical therapeutic development. His ongoing work continues to address critical questions in cardiovascular pharmacology, protective mechanisms against drug-induced toxicity, and the development of novel therapeutic interventions for various disease states, ensuring continued relevance and impact in the field of medical pharmacology.

Assoc. Prof. Onural Ozhan, Inonu University, Turkey